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Cartoon Classics in a Chronic World: The Simpsons •



There are few things in this weed world that we can call timeless and have it be a literal statement. This is most definitely the case when talking America’s most beloved stoner cartoon/television family; The Simpsons.

They started a phenomenon and captured our attention as well as our hearts from the very start, beginning with the opening credits and theme music. Different variations of the people we’ve come to know and love. Ranging from holiday themes to just down right other dimensional. If one thing is for certain the entire city if Springfield, ESPECIALLY The Simpsons was getting substantially higher than the rest of us. The creator chose to show us a view of Springfield first and foremost from the clouds. Seemingly an obvious proclamation, or at the least a high ass innuendo.

I’m sure some of the dank heads reading right now have spent HOURS trying to understand and decipher as well as chatting in forums or even recalling the times you’ve witnessed these yellow bellies predict the future. Most pot smokers refer to this as the Nostradomas effect. Inserting key points and secret locations that only become clearly relevant in years to come.
Cartoon Classics in a Chronic World: The Simpsons
Cartoon Classics in a Chronic World: The Simpsons

Deep levels of thought occur when Mary Jane is your best pal, and the chronic has you so intensely aware you actually become the pineal gland you’ve worked so diligently to open. Scholars could argue that one might be able to pin- point future events if blitzed enough.

Thanks to the hard working immigrants that built this great nation the Quick-E-Mart was born. It’s a corner store, liquor store, Bodega, and hang out spot that is clearly King of all things munchies monster. Apu is just the loving family man and entrepreneur for the job and although stern with the customers , never fails to show himself as team Springfield all the way. From hot dogs to donuts and brews, all ages come to the Quick-E-Mart for supplies and all leave satisfied.

StonerDays Presents Cartoon Classics in a Chronic World

Life would be incomplete without Homer Simpson. DOH!!! Doh is short for doja, and when in turmoil of course that’s who you turn to. He represents the stereotypical stoner, one who refuses to engage in physical activity or be removed from the jaws of couch lock. Homey eats, breathes, and lives in front of the boob tube. Homie never takes a moment to think. He also displays traits of a loving husband and father that has flaws and vices no doubt, but is filled with genuine love regardless..

Homer hits the Doobie Right before kissing Bart, Lisa, and the murdering Maggie then climbs in bed with wife Marge. And lastly letting out one last MMMMMM….GANJA.

Being lost in a chronic cartoon means a D.U.I. is no longer relevant. No trippy Simpsons feature would be complete without mentioning Otto. The infamous bus driver with the hots for Miss Mary Jane. This tie dye wearing smoker has been spotted on many occasions. Emerging from the drivers seat swaddled in a cloud of smoke.

Blazing blunts and choking on dabs and bowls is what we do best, and quality televisions is what the Simpsons brought us to accommodate that great feeling. Thank you Matt Groening, you are now and will forever more be appreciated.

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California safe drug consumption

California Waiting on Governor to Sign Safe Drug Consumption Bill



The idea of a safe drug consumption site is horrible in the first place, there’s no getting around that. By the time we start talking about these things, it means there’s already a pretty big problem that has proliferated out to massive degrees. Right now, California is waiting for a safe drug consumption site bill to get signed by the governor, to combat the ongoing and growing opioid issue. But he’s been holding back… Will he do it?

California looks to be the second state to institute legislation for safe drug consumption sites, so long as the governor doesn’t veto the bill. Welcome to this wholly independent publication focusing on the cannabis and psychedelics spaces of today. We offer the Cannadelics Weekly Newsletter so readers can keep updated on important events, as well as get themselves some great deals on tons of products from vapes and smoking equipment, to cannabinoid compounds like the super-popular Delta 8 & HHC. Find deals in our ‘best of’ lists, and please only buy products you’re totally comfortable using.

What’s a safe use site?

A safe use site – also called a ‘safe drug consumption’ site in California’s SB 57 bill, a ‘harm reduction site’, or a ‘safe injection site’ is a place where drug users can use drugs without threat of legal intervention. This isn’t meant to encourage the use of hard drugs, but instead to offer a safe place for those battling addiction, who are required to take their drug because of their addictions. These sites make it legal to use drugs that are either uniformly illegal, or not meant to support an addiction.

Safe use sites generally offer other services, as well. Like testing kits for fentanyl to ensure a person is using what they think they are; giving out clean needles, and a place to dispose of used ones; and resuscitative services in case of overdose. They are also sites where users can gain information for different programs related to drug addiction or other social services like housing. In general, the sites are meant to act as an oasis for those with drug problems, which allows them to go about their habit, while also possibly accessing help to stop it.

California isn’t the first state to entertain the idea of these programs. In July of 2021, Rhode Island became the first US state to approve a safe use site measure when Governor Dan McKee signed a bill instituting these sites as a measure against that state’s growing opioid issue. Prior to Rhode Island, Philadelphia also attempted to institute safe use sites, but so far has been barred from doing so.

California safe drug consumoption sites

Rhode Island was the first to pass official legislation, but not the first state to enact a program. That designation goes to New York City. The first safe use sites in New York opened in November of 2021, and are in East Harlem and Washington Heights. The sites are backed by Mayor Bill de Blasio, who made the decision to open them, as no formal legislation currently exists. There is a bill circulating in New York’s legislature now, that would institute programs like this throughout New York if it passes.

These sites don’t explicitly come with the expectation of reducing drug use, but they do give a safe place to use the drugs – and possibly more importantly, to keep them away from other populations. The American Medical Association published a study recently about those first two sites in New York, which concluded that the sites have decreased overdose risks, kept use out of the public, and have been useful in providing complimentary services to users in need.

California’s safe drug consumption site legislation

At the end of July, the California Senate re-passed a bill to establish safe drug consumption sites in the state. The bill (SB 57) was amended by the General Assembly in June, requiring yet another Senate vote for passage after edits. This happened in a vote of 21-11, sending the piece of legislation to Governor Gavin Newsom’s desk.

This initial pilot program is meant to go until January 1st, 2028, and only approves sites in the cities of Los Angeles, San Francisco, Los Angeles Country, and Oakland. According to Sen. Scott Wiener who introduced the legislation, “We’re seeing an escalation in overdose deaths. These sites are a proven strategy to save lives & get folks into treatment. It’s time.”

Wiener introduced the legislation originally in 2020, and it did pass the Senate in spring of 2021. Prior to that attempt, a similar bill did go through in 2018, which was vetoed by then-governor Jerry Brown. This time around, though Newsom is against the war on drugs, and a proponent of legal cannabis, there seems to be a hold up in getting the bill signed into law.

Newsom has not actually signed the bill. Though Newsom supports liberal measures, and is a beacon for liberal policy, as a main advocate in the fight for same-sex marriage and cannabis legalization, he still hasn’t signed the bill. If he doesn’t by August 22nd, it will automatically pass into law, though he has until then to sign it or veto it himself. What the holdup is, isn’t clear for sure, but some speculate it has to do with Newsom wanting to run for president in the upcoming 2024 election.

safe injection sites

Where else do safe use sites exist and why?

California and other parts of the US might be starting to adopt safe drug consumption sites, but this isn’t new to other parts of the world. These sites already exist in Canada, Australia, and different parts of Europe, for which there are about 100 sites operating. The largest number in Europe is in the Netherlands, which has almost 40 sites. The country started operating these centers in 1996, and was able to subsequently lower the amount of overdose deaths in the country. Canada opened its first site as far back as 2003 in Vancouver.

In Canada, between the years 2017-2019, there were two million visits to these safe use sites. As of last year the country had 39 operational safe use sites, which accounted for an expected daily rate of 3,000 people across sites. The busier sites operating in Canada often have up to 500 visits a day, according to Health-Infobase.  

These pilot programs were not put in place for drugs like cannabis, but rather to combat the increasing opioid epidemic which is claiming so many lives. However, it technically operates as a place where cannabis can be used freely as well. The real culprit is not illegal drugs like heroin (which started the whole safe-use thing in the first place), but prescription opioid medications like fentanyl, which are still being written in large quantities.

Just how many deaths are we talking about? In May of this year, the CDC released preliminary data, which put the overdose rate for 2021 at 107,622. That’s total overdose deaths, but seeing how 68,000 of 2020’s 93,000 overdose deaths were opioid-related, it gives a pretty good idea of just how impactful opioids were in the 2021 number.

Why is this considered a pharmaceutical issue? Of the close to 71,000 overdose deaths of 2019, heroin overdoses accounted for under 15,000, while synthetic opioid overdoses (the big pharma drugs like fentanyl and oxycodone) accounted for 48,000. Of course, its actually been noted by the CDC that heroin overdose deaths decreased by 7% from 2019-2020, indicating that a raised overdose rate, is related to the pharma-produced synthetic opioids only.

Is this the best option?

This is so much of a pharmaceutically-made problem, that it makes recent moves, like President Biden sending out a memorandum on why Colombia should still be attacked for its illicit drug trade, seem rather odd. If Biden is saying Colombia is that dangerous, when its not where the drugs causing the deadly issue are coming from…then why act like that’s the big problem, while simultaneously allowing pharmaceutical companies to continue selling opioids, and for doctors to continue prescribing them?

Drug overdose deaths

If the drug problem is so bad and rising despite a failing war on drugs, then it seems the US should be blocking all pharmaceutical opioids in general, and leaving countries like Colombia out of it. Not only did Biden send that memorandum, but he did it the day new Colombian president Gustavo Petro started talking about ending the war on drugs, and finding better means that won’t result in a bunch of dead Colombians. Sounds like Biden would prefer dead Colombians to other, more useful, and more sense-making, options.

Like ketamine. How ketamine has been so completely left out of the conversation, while memorandums are given to the defense secretary to continue bombing Colombians suspected of having a part in the illicit drug industry, is insane. Yet research is out on ketamine’s ability to help with both acute and chronic pain, comparably to opioids, and that it does so without the same ability for addiction. In fact, it’s been shown to help with the obsessive thoughts that go with addiction, making it an even more useful tool for getting people off of these synthetic opioids. Add onto this that short term infusions have shown to net pain-relief results for up to several weeks at a time, and it makes the idea of safe use sites, or large-scale drug decriminalization measures of hard drugs, the worse options that will keep people hooked, rather then help them end their addictions.


Whether Newsom signs the California bill for safe drug consumption sites, vetoes it, or simply lets it pass into law, the problem doesn’t go away. If America really wants an answer to this growing catastrophe, it will have to think way more logically than making something unwanted, more socially acceptable; and get to the reasonable alternative measures that can actually end this.

Hello readers! We appreciate you joining us at, a top choice news platform for independent coverage of the growing cannabis and psychedelics landscapes of today. Come by the site whenever possible for updates on current and world-changing events, and head over to the Cannadelics Weekly Newsletter, so you’re always up on what’s going down.

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cannabis digestive health

Can Cannabis Rebalance the Microbiome?



Digestive issues are amongst the most common disorders in the world, which is why researchers are always keen to discover new therapies to treat gastrointestinal (GI) conditions. The discovery of endocannabinoid system receptors in the GI tract has led researchers to examine links between cannabis and the gut, to ascertain if cannabinoid compounds can be used to rebalance an unhealthy microbiome.

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What is the Microbiome?

Trillions of bacteria, fungi and viruses live along the GI tract and on the skin. In fact, there are more bacterial cells in the body than human cells, about 40 trillion bacteria to 30 trillion human cells, meaning the body is made up mostly of these microbial organisms, known collectively as the microbiome. When referring to the microbes in a specific area of the body, they’re known as microbiota.

The microbes in the GI tract are referred to as gut microbiome, and are mostly found in a pocket of the large intestines, known as the cecum. Though there are many types of microbes, bacteria are the most studied. There are more than 1,000 types of bacterial microbes in the gut microbiome, and each plays a vital role in maintaining overall health.

In the past, it was thought that the gut was only responsible for digesting food, but now it’s known the interaction between the gut microbiome and brain plays such an important role in overall wellbeing, the stomach has been dubbed, the “second brain.” As food is digested, enzymes are created, firing neurotransmitters that influence everything from weight, blood flow, bone growth and heart health to immunity, libido, sleep and mood.

Poor gut health can cause an array of problems, leading to obesity, heart attack, stroke, type 2 diabetes and high cholesterol. In addition, the gut influences brain function through the Vagus Nerve, sending a constant stream of messages in the form of neurotransmitters, signaling the brain to release hormones that regulate body and mental health. Other outcomes of poor gut health include anxiety and depression.

What is the Endocannabinoid System?

The endocannabinoid system (ECS) was discovered by the Israeli chemist Raphael Mechoulam in the early 1990s, as part of his research into cannabis compounds. In 1992, Mechoulam’s lab isolated the first endocannabinoid, a molecule now classified as a CB1 receptor partial agonist, and named anandamide. Soon after, another endocannabinoid was discovered, 2-arachidonoylglycerol, or 2-AG.

In fact, there are hundreds of endocannabinoids active throughout the body, but these two are the most studied. Endocannabinoids are types of molecule produced by the body that act on receptors to keep all systems working optimally.Endocannabinoids behave differently from other neurotransmitters. Neurotransmitters are stored in vesicles and released when activated by a presynaptic neuron, acting postsynaptically. By contrast, endocannabinoids are produced on demand, where and when needed. They are released by postsynaptic neuron and act presynaptically. They bind to receptors to activate signaling.

working out with weed

There are two main forms of receptors: CB1 receptors, found mostly in the central nervous system (CNS) and CB2 receptors, found in immune cells. CB1 is one of the most abundant G-protein-coupled receptors in the CNS. CB1 receptors are present in the neocortex, hippocampus, basal ganglia, cerebellum and brainstem.

As well as immune cells, CB2 receptors are found in the peripheral nervous system, and are associated with inflammation, addiction and synaptic plasticity. Endocannabinoids can bind to either receptor. The effect depends on where the receptor is located and which endocannabinoid binds to it.

Links between ECS and the Microbiome

Much research needs to be done to understand the full scope of the ECS, but one of its functions appears to be a modulator between the digestive, nervous, and immune systems. In the same way that the gut microbiome works to maintain overall wellbeing, or homeostasis (a state of balance between the body’s organs), so too does the ECS.

Research links the ECS to the following functions: appetite, digestion, metabolism, inflammation, chronic pain, mood, learning, memory, motor control, sleep, heart health, liver function, stress and reproductive health. As the gut microbiota also plays a key role in these functions, it easy to see how an imbalance in one system can have knock-on effects to the other systems.

For example, endocannabinoids might target CB1 receptors in the spinal nerve to relieve pain. Others might bind to CB2 receptors in immune cells to signal the body is experiencing inflammation, a common sign of autoimmune disorders. CB1 receptors have a direct action on the gut, and have been shown to modulate intestinal motility.

More than that, a growing body of evidence now confirms the presence of a “gut-endocannabinoid axis,” which determines the integrity of the gut barrier by influencing both gut barrier function and intestinal permeability. Research has shown that increases or decreases in certain endocannabinoids affect the number of good probiotic bacteria in the gut. Because cannabis is a phytocannabinoid that acts on the ECS, it has the capacity to bridge the ECS and gut microbiota.

Can Cannabis Balance the Microbiome?

In vitro assays (cell research in glass) have shown that cannabis has antimicrobial properties. The human gut contains 4 main phyla: Firmicutes, Bacteroidetes, Actinobacteria, and Proteobacteria, of which Firmicutes and Bacteroidetes are linked to obesity and colorectal cancer.

A high Firmicutes: Bacteroidetes ratio is typical with obesity, and new research shows a balanced ratio can be restored in mice using the psychoactive cannabis compound, Delta-9-tetrahydrocannabinol (THC.) In obese mice, the gut microbiota modifies endocannabinoid signaling, resulting in increased gut permeability, inflammation and fat storage.

THC has been shown to block this effect by increasing the presence of bacteria called Akkermansia mucinphila, which control fat storage and metabolism to facilitate weight loss. This bacterium can also strengthen signaling between the gut and the brain, and strengthen the gut barrier. It also linked to improved glucose tolerance and glucose metabolism.

Research on long-term users of cannabis has shown that users display Prevotella: Bacteroides ratio 13-fold lower than non-users. Though further research is required to assess the full implications of this finding, what is clear is that cannabis use leads to alterations in gut microbiome, which due to the interconnectivity of the ECS, affects other physiological systems, including brain function.

It’s also clear that there are links between the gut microbiome and both gastrointestinal and neurodegenerative disorders. The ability of THC to change the gut microbiome, by increasing the number of healthy bacteria that protect against obesity and associated conditions, suggest its restorative capacity to balance the microbiome.

Finally Thoughts on Cannabis and the Microbiome

A 2016 article that reviewed over 10 years of research suggests the theory that endocannabinoid deficiency could be the source of autoimmune disorders including fibromyalgia and irritable bowel syndrome, as well as migraine. However, because the full scope of the ECS is not understood, medical applications are still evolving.

The drug rimonabant was developed to aid weight loss by blocking the CB1 receptor. The thinking was that if the ECS controls hunger, a drug that blocked signaling could cause weight loss. The drug worked in this regard but because the ECS is so connected to other functions, rimonabant also caused some nasty side effects on mood. People who took reported feeling suicidal. Rimonabant was removed from the market.

However, it’s easy to imagine that with better understanding of the ECS and the workings of endocannabinoids, it will be possible in the future to develop cannabis medications with more direct actions that provide relief by alleviating symptoms of digestive orders and/or rebalance the microbiome.

Welcome all! Thanks for dropping by, a top offering for comprehensive news covering the burgeoning cannabis and psychedelics industries. Stop by daily for a dose of news on these dynamically changing fields, and sign up for The Cannadelics Weekly Newsletter, so you’re up on everything important going on.

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Hexahydrocannabinol 101: HXC vs HHC



Although still considered a somewhat less common alternative cannabinoid, HHC – or Hexahydrocannabinol – has been gaining popularity over the last year. To the point that it’s currently undergoing a rebrand, so to speak. Some companies have started referring to HHC, as HXC. Learn why the switch to HXC is happening. 

To stay current on everything important happening in the industry, subscribe to The Cannadelics Weekly Newsletter. Also, it’ll get you premium access to deals on cannabis flowers, vapes, edibles, and much more! We’ve also got standout offers on cannabinoids, like HHC-O, Delta 8Delta 9 THCDelta-10 THCTHCOTHCVTHCP HHC, which won’t kill your bank account. Head over to our “Best-of” lists to get these deals, and remember to enjoy responsibly!

What is Hexahydrocannabinol (HHC/HXC)? 

All abbreviations aside, let’s focus on the basics here: what are hexahydrocannabinols? In short, they are another group of psychoactive cannabinoids that are very similar to tetrahydrocannabinols. HHC is basically a simplified version of Delta 9 THC. Both HHC and THC have very similar molecular structures and comparable effects. With HHC, all the double bonds have been broken and replaced with hydrogen (AKA hydrogenation). It was discovered during research in the 1960s and 70s in which the goal was to find the most basic cannabinoid-like substances that could still bind to CB receptors.   

There is a biologically active naturally occurring (−)-hexahydrocannabinol, as well as its synthetic enantiomer (+)-hexahydrocannabinol. The synthetic HHC, which can be found in spice, has the chemical formula: 9-Nor-9β-hydroxyhexahydrocannabinol, and the natural variety, found in trace amounts in cannabis pollen, goes by the formula: 6aR,9R,10aR-Hexahydrocannabinol.    

In addition to the natural and synthetic HHCs, a couple of more potent analogues and isomers that have been created, as well as new discussion regarding the possibility of more chain lengths and combinations like HHCV, HHCB, HHCH and so on. These are the same chain length variations we see in all the different THCs.  

Now, keep in mind that these are all synthetic cannabinoids – but in cannabis, the definition of “synthetic” can mean one of two things. First, synthetic cannabinoids are compounds that do not exist in nature and must be created in a lab, like THC-O. Also, a synthetic can be a cannabinoid that does exist in nature, but in such minimal amounts that in order to manufacture enough for it to be used in consumer products, it must still be synthesized in a lab, like Delta 8 THC. HHC-O falls into the first category, while HHC belongs to the second. In cannabis plants, HHC is found in trace amounts in the pollen. Then we have HHC-O, which is the acetate version of HHC, and HHC-P which is the carbon version.  

We’re seeing a small influx of new, HHC-P products, hitting the store shelves, but it’s close to impossible to find any information about this cannabinoid that comes from a neutral, fact-based party rather than from the companies who are selling it. It’s likely because, the companies selling the compounds are also the ones who are creating them in the first place, and no one else really knows about these compounds or has had the opportunity to study them yet. 

What’s in a name? HXC vs HHC 

Just to make It perfectly clear, HXC and HHC are the same thing. Simply put, HHC is undergoing a rebrand, with a few select companies now selling HXC, HXC-O, and HXC- P… instead of HHC, HHC-O, and HHC-P. It’s hard to tell how many companies will begin doing this, but because a couple of the bigger industry brands like Delta Extrax and Cake are doing it, it’s likely to catch on.  

According to our friends over at Delta Extrax, “As cannabinoids gain popularity, so does the misinformation about them. You can look at this slight change in abbreviation as an upgrade and those who don’t adapt get left behind. Another big reason why the name upgrade occurred is that HXC is the abbreviated word for Hexahydrocannabinol (HHC).” 

It’s a simply but straightforward reason. I personally cannot think of any other cannabinoids getting a new name or rebranding, as there is usually some scientific basis to their names and acronyms. But it’s possible that we may see more of this in the future, and perhaps this is signaling a time when consumer products start to veer away from their chemical descriptions and start using more marketable names.  

HHC/HXC and drug testing

When it comes to cannabis, standard urine tests are used to detect use ranging from roughly 1 to 45 days. Occasional users will typically be clean after 1-5 days, regular light users will take about 1-3 weeks, and for heavy daily users, expect 4 to 6 weeks to get clean. Contrary to popular belief, standard urine tests don’t screen for the THC (tetrahydrocannabinol) in cannabis, but rather, they detect the metabolites created by the human body when we are exposed to THC.

This class of metabolites is known as THC-COOH. These metabolites are inactive, so drug testing only measures exposure, NOT impairment.THC-COOH, or “carboxy THC” is the most common name for this metabolite. It’s the second THC-metabolite formed in our bodies, following hydroxy-THC, immediately after exposure. THC-COOH is lipid-soluble, meaning it’s stored in our fat cells making it detectable in our systems for much longer than other substances, those that are water soluble for example.

One of the more interesting and appealing attributes about HHC/HXC, is that it is believed to not show up on a drug test, because it does not trigger the same metabolites in the body as tetrahydrocannabinols. Now, this is where things get a bit sketchy… it’s quite difficult to find products that are pure HHC/HXC. Even when advertised as such, many of these products contain trace amounts of Delta 8, Delta 9, and other THCs, in which case, the user would fail their drug test. To be safe, all cannabis products should be avoided if you have an important drug test coming up.

Companies that have switched to HXC – and what consumers are saying about it

So far, I’ve only discovered two major companies and one smaller brand that are selling HHC products as HXC. The two household names are Cake and Delta Extrax, and the lesser known company is Medusa Delta 8 – all of which are selling some HXC vape devices.

Examples of some HXC products you can find at Delta Extrax: SFV OG HXC + HXC-P 2 Gram Disposable, Space Candy HXC + HXC-P 2 Gram Cartridge, and Tropical Zkittlez HXC + HXC-P 2 Gram Cartridge. At cake, you can check out HXC disposables in a variety of different strains and flavors including: Animal Cookies, Banana Runtz, Blue Dream, Kush Mints, Pineapple Express, Gelato 41, Dragonfruit Rosin, and many more.

The Delta Extrax products are new, so reviews aren’t out yet, but the Cake HXC products have been around for a few months, and the reviews are mixed. As with most alternative cannabinoid products, some people love them and some don’t. Some say they have little effect, while others believe they’re stronger than THC. Case in point, everyone has different body chemistry and tolerances, and may react differently to the same compound or product.


Once again, HXC and HHC are the same thing. HXC is the new name/acronym given to hexahydrocannabinol by a small number of companies who sell alternative cannabinoid products. Whether you’re looking for products or information on HXC, your best bet is to check back here or subscribe to our weekly newsletter for all the latest industry updates.

Welcome all! Thanks for dropping by, a top offering for comprehensive news covering the burgeoning cannabis and psychedelics industries. Stop by daily for a dose of news on these dynamically changing fields, and sign up for The Cannadelics Weekly Newsletter, so you’re up on everything important going on.

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