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Esketamine in the UK – CBD Testers

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The world of drugs is constantly shifting and changing. It seems like, finally, government’s are beginning to open their minds to the many magical benefits of drugs, and are no longer being blinded by the potential recreational uses. The truth is, almost all drugs that people may buy from street dealers or off the dark web – are also used daily in medical practices.

This is the case with heroin, NOS, cocaine, MDMA and ketamine. What some of these drugs offer are quick relief from mental and physical pains, which usually prescribed medicines do not have the capability for. This is the situation with esketamine. Since 2019, esketamine has been medically legal in the UK due to its proven benefits for treating depression. But how has it been going? How easily accessible is it? And, more importantly, what even is esketamine? The UK isn’t championed by the rest of the world for their open-drug policies, but perhaps this is a start. 

Ketamine and esketamine therapy are all the rage, but they’re still not as easily accessible as cannabis. Fortunately, there has been more focus on these compounds in recent years and the market is poised to explode in the very near future. Remember to subscribe to The Psychedelics Weekly Newsletter for more articles like this one. And save big on Delta 8Delta 9 THCDelta-10THCOTHCVTHCP & HHC products by checking out our “Best-of” lists!


What is Esketamine?

Esketamine is an isomer of ketamine, which essentially means that it has a very similar chemical structure, despite a few certain atoms. For those of you who aren’t aware, ketamine is both a popular recreational and medical drug. Ketamine has been found to be an anesthetic and anti-depressant and was actually used to treat injured Vietnam soldiers. Not only that, but Ketamine is often referred to as a ‘horse tranquiliser’ as it’s often used in veterinary practices to anaesthetize bigger animals. Ketamine has also been found to have euphoric effects, which is why it’s often used as a party drug, and is also why it’s not being further considered as a potential antidepressant. This is why Esketamine has not been created. Esketamine is actually a more potent version of ketamine.

“…blocks N-methyl-D-aspartate (NMDA) receptors and interrupts the association pathways of the brain, resulting in dissociative anaesthesia and analgesia and in restoration of neural pathways regulating mood and emotional behaviour.”

Now, this might sound a little bit scientific, but actually esketamine works quite simply. The drug is believed to act on a brain chemical called glutamate, which is thought to restore connections between brain cells, which supposedly shrink during long periods of depression. This regrowth leads to the production of healthy serotonin, which affects the emotions of a person. 

How It’s Taken

Esketamine, unlike ketamine, is taken in the form of a nasal spray called Spavato. It’s taken alongside an oral anti-depressant. The patient will usually seek a prescription, and if they’re able to get one, they will embark on two key stages of treatment. 

Step 1

Step 1, also known as the induction phase, consists of the user taking two treatments per week, for a full month. The amount of sprays and dosage will be different depending on the patient. 

Step 2

Step 2, also known as the maintenance phase, will consist of the esketamine dosage being slowly reduced to once a week, or even perhaps once a fortnight. This is to see how bad the depression flares up with less of the medication. 

Esketamine & Depression

Depression is a mental health problem that can affect 1 in 5 adults in the UK. The symptoms of depression can include: feeling low, suicidal thoughts, anxiety, lack of appetite and a loss of hope. Most doctors prescribe anti-depressant drugs to deal with depression. These drugs are known as SSRIs and they help to keep more serotonin in the brain. Serotonin is a neurotransmitter that carries signals between nerve cells; it’s thought to have a positive influence on mood. SRRIs stop serotonin from being reabsorbed after it carries these signals, which keeps more serotonin in the body. However, esketamine does not work like this. The issue with SSRIs is that they can take quite a long time to take effect – perhaps a few months – and for some people they don’t work at all

“As many as two-thirds of people with depression do not respond to the first medication prescribed and are considered to have TRD. TRD is a term used to describe depression that has failed to respond to at least two different antidepressants.”

This is where esketamine comes in. TRD stands for treatment-resistant depression and essentially means that the usual SSRI treatment is obsolete for them. Esketamine works differently to mainstream antidepressants, it instead increases the levels of glutamate – which has the largest quantity of chemical transmitters in the body. The new drug is thought to be the future of antidepressants as it has robust effects within a few hours and the effects are long lasting. Eskatimine

“…Is one of the first “rapid acting” drugs for depression and the first drug in decades to target a new brain pathway. Unlike conventional antidepressants, which take weeks or months to take effect, ketamine has been shown in some patients to have enduring effects within hours.”

The benefits of Eskatimine is undoubtable, and this has caused many countries to turn their heads towards it as a potential, more mainstream treatment option. That is why the UK, among other countries, have begun this process. 

Is Esketamine Legal in the UK?

Yes. As previously mentioned, esketamine is a more potent, and slightly different version of ketamine. Ketamine is of course one of the most popular party drugs in the UK and in many countries. However, due to ketamine’s street-drug credit, many governments are fearful of using it as a viable antidepressant alternative. Nonetheless, in 2019, things changed. Spravato had been subject to many medical trials with those suffering from treatment-resistant depression and now...

“..It has been deemed a safe treatment and was licensed in the UK for use in late 2019, as well as approved in the USA by the Food and Drug Administration (FDA) for use in early 2019”

The companies that are the creators of the drug were Johnson & Johnson in the US, and Janssen-Cilag in the UK. Eskatmine in the form of a nasal spray is legal and available from specific psychiatric prescribers and pharmacists within the UK. However, like with all legalization, it’s never just as simple as ‘here you go, whoever needs it, come get it’. The truth is that, just like medical cannabis in the UK, esketamine is not an easy substance to get ahold of, and it’s not cheap either. So, let’s take a little look into how the UK is doing since legalizing this substance in 2019. 

How’s It Going Since 2019?

Legalizing esketamine for medical use was a big leap for the UK and highlights a potential but a slow shift in drug policy. Nonetheless, the sad truth is that – whilst the substance could be having huge medical benefits for those suffering with TRD – it’s currently very difficult to get a prescription. Almost all of the limited prescriptions of Spravato come from private institutions, and the prices are not cheap. Supposedly, the current price of a 1 x 28mg nasal spray bottle is £163. In addition, to access esketamine you need a written prescription from a private psychiatrist. Psychiatrists are a luxury and are not something that the majority of people are able to afford. 

The NHS is the UK’s free health care service, and it is perhaps the UK’s pride and joy. However, it’s constantly underfunded by the Conservative government. The NHS do not currently back esketamine in the UK, as they don’t see it as being  a cost effective option for them. Due to the price of it, it’s easier for them to continue prescribing other antidepressant medication than spravato. However, there is one specific case where the NHS has prescribed the drug. And that is in, of course, Scotland. Scotland is known to be the liberal side of the UK. 

“the Scottish Medicines Consortium (SMC) accepted the use of esketamine (Spravato; Janssen) nasal spray for use within NHS Scotland for adults with treatment-resistant major depressive disorder on 8th September 2020.”

Whilst this isn’t massive, it’s still a step in the right direction. The hope is that, going forward, the government will help the NHS to back the spravato medication and finally allow people who need it to have access to it. However, it could still be a long road ahead.

Conclusion – Esketamine in the UK

Esketamine is an example of a drug that has forced itself to be noticed by medical professionals and government officials due to its undoubtable worth. Even the UK, who aren’t the leaders of drug acceptance, have decided to give it esketamine shot. Whilst it is not the cheapest and most accessible antidepressant medication, the hope is that now it’s been accepted for medical use, it’s only a matter of time before more people have access to it. The hope is there. Let’s wait and see.

Hello to all. Welcome to CBDtesters.co, your #1 web source for cannabis and psychedelics-related news, offering the most thought-provoking and current stories going on today. Give us a visit frequently to stay on top of the always-changing world of legal drugs and industrial hemp, and remember to check out  The Psychedelics Weekly Newsletter, so you’re never late on getting a news story.

Disclaimer: Hi, I’m a researcher and writer. I’m not a doctor, lawyer, or businessperson. All information in my articles is sourced and referenced, and all opinions stated are mine. I am not giving anyone advise, and though I am more than happy to discuss topics, should someone have a further question or concern, they should seek guidance from a relevant professional.





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Seattle Is Biggest City to Decriminalize Magic Mushrooms

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The psychedelics boom is certainly underway, with the biggest individual city yet joining in on it. With Seattle now on board, the landscape of magic mushroom use in the US has inched up further, which may just lead the way to a national legalization, at least medically. So what’s the deal with Seattle, and how exactly did the city decriminalize magic mushrooms?

With Seattle as the latest city to decriminalize magic mushrooms, the world of psychedelics is expanding out further. And this on top of the massive progress of the cannabis industry! A few years ago, the only thing to smoke was standard weed. These days, compounds like delta-8 THC, delta 10, THCV, HHC, THCP, THC-O and even hemp-derived THC are flying off shelves, and giving users that many more options. We’ve got great deals for you to check out for all kinds of hemp-derived cannabis compounds including, so take a look at our ever-evolving catalogue – The Delta 8 Weekly Newsletter – and pick your perfect product.


What happened?

On Sunday, October 4th, the city council of Seattle unanimously voted to decriminalize psilocybin, the active component of magic mushrooms, as well as other plant-derived psychedelics like ayahuasca. This decriminalization applies to non-commercial use, although no decriminalization measure technically applies to commercial use, as this requires an actual legalization.

The new measure in Seattle to decriminalize magic mushrooms means that arrests and prosecutions for possession and use of these compounds, has been lowered in priority for police, though the substances still technically remain illegal. Seattle became the largest independent city to decriminalize these drugs, when the vote was made. As of right now, all substances to be decriminalized by Seattle, are still Schedule I on the DEA’s Controlled Substances list.

At least part of the reason this measure came up at all, is because magic mushrooms, and other plant-based psychedelics, are actually used for spiritual purposes. This was clearly not the only reason though, as council member Andrew Lewis stated: “These nonaddictive natural substances have real potential in clinical and therapeutic settings to make a really significant difference in people’s lives… This resolution really sets the stage as the first significant action in the state of Washington to move this policy forward.”

magic mushroom decriminalization

Lewis went even further, telling Bloomberg of the decision in Seattle to decriminalize magic mushrooms, “There’s a huge demonstrated potential for these substances to provide cutting-edge treatments for substance abuse, recovery from brain injuries and other issues… I want to make sure we’re following the science in our policies around regulating these substances.”

Is it legally binding?

Unfortunately not, which means in actuality, Seattle didn’t decriminalize magic mushrooms. Seattle’s vote is considered a non-binding resolution, which means it was voted on and adopted, but cannot become an actual law. This means, it’s really not a law, but only a general recommendation, something that should be taken into account. The resolution states: “the investigation, arrest, and prosecution of anyone engaging in entheogen-related activities should be among The City of Seattle’s lowest law enforcement priorities.”

It also goes on to state that “full decriminalization of these activities” is supported by the council. While this is all fine and good, and certainly a step in the right direction, I personally wonder if the lack of a legal resolution could end up creating issues, particularly if some law enforcement do not feel the same way. How that will actually go down remains to be seen, as there is no legal directive actually stopping law enforcement from continuing as they were.

Some council members saw this aspect of the decision in Seattle to decriminalize magic mushrooms as an issue as well, like Kshama Sawant. Councilwoman Sawant stated, “I am a little confused by this resolution… We have not pushed for resolutions in place of ordinances where it is possible, realistic, and necessary from a political and moral standpoint for the council to have an ordinance passed. I fail to see what the plausible reasons are for councilmembers who claim to support this issue to let an ordinance which takes concrete action sit in the city’s computers unintroduced, and instead push a resolution which only has the power to make requests.”

What other places have legalized magic mushrooms?

Magic mushrooms, and psychedelics in general, have gotten much main stream attention of late, following in the foot steps of the cannabis industry, which itself has gone from demonized, to pretty well accepted, in the last decade. When Seattle passed its decriminalization measure, it became only the latest of many locations to do so. It joins Denver, the first city to make such a law three years ago (May 2019), and Oakland (psilocybin and peyote) and Santa Cruz in California which also set measures that same year and the next.

Ann Arbor, Michigan was next, decriminalizing entheogenic plants or plant compounds also in 2020, followed by Washington DC, which decriminalized all psychedelics that are plant and fungus based in 2020. January 2021 started with Washtenaw County, Michigan following DC’s lead, with Somerville, Massachusetts decriminalizing entheogenic plants including mushrooms and ibogaine later that month. In February of this year Cambridge, Massachusetts decriminalized, followed by Northampton, Massachusetts in April. This October, not only did Seattle join the ranks, but Arcata, California, and Easthampton, Massachusetts did as well. Most of these have an actual legal basis, whereas Seattle does not.

entheogens

And then there’s Oregon. In November of 2020, Oregon included two ballot measures called Measure 109, and Measure 110 which worked to decriminalize psilocybin state-wide (along with other drugs), as well as legalizing its medicinal use. This made Oregon the first state to allow for the legalization of psilocybin (or any psychedelic outside of esketamine which was passed federally), in any capacity. The initiative had qualified to be on the ballot by May 26th of 2020, and officially passed on November 3rd, when the measure was voted on by the public during the general elections.

Are all psychedelics illegal federally?

Nope, although most people might not realize this. Not only has a compound like DXM (dextromethorphan) been in products like cough syrups since 1958 – the entire reason behind the term ‘robotripping’, but in testing, it has shown very similar characteristics to psilocybin from magic mushrooms. I can honestly say from my own personal experiences, that the only positive benefit to being sick when I was younger, was using Nyquil for that awesome cough syrup high. Somehow or other, despite all other psychedelics being illegal, DXM slipped through the cracks years ago, becoming one of the most widely used psychedelics in America, with literally no requirement for over-the-counter purchases.

For those unfamiliar with the name ‘DXM’, it’s a dissociative drug of the morphinan class. Morphinans are generally naturally occurring components like morphine and codeine, but includes chemical derivatives as well like DXM. DXM doesn’t bind to opioid receptors like other morphinans, which sets it apart from the rest of the class. Instead, its mechanisms of action include being a nonselective serotonin reuptake inhibitor, and a sigma-1 receptor agonist among other functions. In low doses it makes a person feel pretty good. In high doses it acts as a dissociative hallucinogen.

DXM isn’t the only federally legal psychedelic. Ketamine and esketamine make the cut as well. Ketamine is only approved for certain medical uses, particularly as an anesthetic. However, its close cousin esketamine, was approved in 2019 as the first non-monoamine anti-depressant, for use medically. This was updated the following year when it was cleared for use with suicidal thoughts as well, something that requires an incredibly quick action from a drug, which esketamine is known for.

While esketamine therapy is becoming more well-known, and even covered by insurance, clinics are taking time to pop up in many locations, and access is still limited. Beyond this, many doctors will never inform patients this is an option, either for their own reasons of confusion over the compound, (likely from years of government smear campaigns), or their general lack of knowledge about the option in general. Even so, esketamine represents the first major step in formally legalizing medical psychedelics, though DXM proves the US government is pretty cool with letting them through if mass amounts of money can be made. Though I couldn’t find specifics on revenue for this specific compound, considering over 100 over-the-counter cold and flu products contain it, I’d say it holds a massive value.

Into the future

One thing to keep in mind, is that the FDA has already awarded ‘breakthrough therapy’ designations to three companies operating in the psychedelics field, and covering two different compounds. This designation is given when a company is doing research that shows a compound to be more beneficial than standard options, for which the FDA agrees and wants to see products get to market. In 2017, the designation was given to the organization MAPS (Multidisciplinary Association for Psychedelic Studies). MAPS is currently in phase III of it’s studies, which were put together in conjunction with the FDA to ensure that results would meet regulation.

magic mushrooms depression

In 2019, this same designation was given to Compass Pathways, and Usona Institute, for their respective studies into psilocybin for major depression. The idea that a US federal agency has awarded this designation repeatedly to compounds in Schedule I of the Controlled Substances list, says quite a bit about the US’s intention to eventually legalize them.

Further to this, other states are also working to push through bigger measures, much like Oregon, or even further. A bill was introduced in Michigan in September 2021, which seeks to legalize recreational psychedelics. SB 631 is currently in the Senate, and has been referred to the Committee on Judiciary and Public Safety. California, not to be outdone, has its own plans, hoping to institute a ballot measure in 2022 for the complete legalization of the possession and sale of psylocibin statewide. The California Psilocybin Legalization Initiative would allow a vote by residents in order to pass into law.

Conclusion

Though Seattle’s new policy is certainly lacking in terms of legal backing, it does put a step in the general right direction of loosening the prohibition of psychedelic compounds. Regardless of specifics, it does say something that a city as large as Seattle has now put in a measure to decriminalize magic mushrooms.

Hello and welcome! Thanks for stopping by CBDtesters.co, your one-stop-shop for all the best and most relevant cannabis and psychedelics-related news globally. Take a read-thru every day to stay aware of the ever-in-flux world of legal drugs and industrial hemp, and remember to sign up for The Delta 8 Weekly Newsletter, so you always know what’s going on.

DisclaimerHi, I’m a researcher and writer. I’m not a doctor, lawyer, or businessperson. All information in my articles is sourced and referenced, and all opinions stated are mine. I am not giving anyone advise, and though I am more than happy to discuss topics, should someone have a further question or concern, they should seek guidance from a relevant professional.





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KETAMINE: What Is It? – CBD Testers

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The world of new drugs and drug fads move quicker than anyone can keep up with. In fact, if you even tried to understand what ‘the kids’ are taking these days, you’d probably end up both confused and intoxicated quite quickly.

There used to be a time where cocaine, cannabis and ecstasy was all anyone spoke about. However, nowadays, the world of drugs has opened up excessively. The likes of GHB, M-CAT, ketamine, mushrooms, acid, crystal meth and unlimited others are all being taken around the world. Each drug has its own story and its own positives and negatives. So what about Ket, K, or Ketamine? The horse tranquillizer that many people have decided to take, despite not being horses. What is it and what does it do? Let’s delve into the world of ket. 

Ketamine is a drug with a very interesting history and reputation, but, like many other mind-altering compounds, it does have a place in both the worlds of the therapeutics and recreation. To learn more about cannabis and psychedelics, make sure to subscribe to The Delta 8 Weekly Newsletter for more articles like this one, as well as exclusive deals Delta 8Delta 10 THCTHCVTHC-OTHCPHHC and even on legal Delta-9 THC!


What is Ketamine?

Ketamine, like most drugs, has many different names: ket, wonk, donkey dust, K, Klein and many others. There are unlimited names for most drugs as often all it takes is for someone to invent a new one whilst they’re high, and usually it will stick. Ketamine, or often shortened to just ‘ket’, is an anesthetic that is used by both doctors and veterinarians. The reason why most people refer to ket as ‘horse tranquillizer’ is because it technically is. However, ketamine is also used as anesthetic for most animals. The reason why it is especially popular with horses is because doctors find ketamine to be a helpful way to deal with larger animals. 

Most people would say that all drugs have to sit in one of two categories: uppers and downers. Whilst ecstasy would be described as a stimulant or upper, alcohol would be considered a depressant or downer. Ketamine is part of the latter category: the downers. That is because it is literally anaesthetizing the user. Whilst there are also feelings of euphoria, the overarching feeling is weighty and thus it is a depressant, not a stimulant. But what does this drug look like? 

What Does It Look Like?

Although Ketamine can be used as a clear fluid by those in the medic world, on the streets – Ketamine is most commonly found as a white powder. It looks very similar to cocaine, but don’t be fooled, they are very different drugs. They are also very different in their potencies. In fact, if you were to take a line of ketamine with a cocaine amount, you’d most definitely be surprised by the strength. It wouldn’t be a good idea, that’s for sure. Ketamine is most commonly sniffed either through a note, or by using a key. Due to its strength, it is often ‘keyed’ because the amount you can place on a key and sniff is usually enough. 

Although Ketamine can resemble cocaine, it’s important to remember that they both smell and taste different. For those who are well versed in the worlds of drugs, the differences are pretty obvious. Plus, cocaine can sometimes be sold in rocks, which means you have to crush it first. Ketamine will never be sold in rocks, always in fine powder. However, the similarity between the two substances is definitely something to keep an eye on. Getting the two mixed up will most likely lead to something not very nice. In fact, it could lead to the infamous ‘K-Hole’. Don’t worry… we’ll get on to that later. 

The History of Ketamine

The history of Ketamine is a surprisingly interesting one. In 1956, a drug called Phencyclidine was found to be a very good anesthetic for monkeys. It was so useful that doctors then began using it on humans. However, there was a problem. The problem was that those using this drug were beginning to experience side effects. With an ideal anesthetic, the patient will wake up and feel normal after. However, with Phencyclidine, patients were waking up with loss of sensations in their limbs and other senses. This was of course an issue. In conclusion, Phencyclidine was considered to be a bad anesthetic, despite the initial successes. It was then that Dr. Calvin Lee Stevens decided to mess about with the substance, with the aim of synthesizing a better alternative. One without the bugs, but with the positives. Reset Ketamine speaks about what happened next: 

“The compounds he synthesized were sent to pharmacological testing in animals, and one compound in particular was found to be a successful, short-acting anesthetic. Selected for human testing, it was titled CI-581 and is what we now call ketamine. Ketamine was named because of the ketone and the amine group in its chemical structure”

After the creation of this new substance, Ketamine took off and was used for a variety of different things. Obviously it was used as an anesthetic on all types of animals and humans. But not only this, Ketamine was found to have euphoric and antidepressant qualities. In fact, Ketamine was used on injured soldiers during the Vietnam War. This is because it was known to help with short-term pain. In addition, Ketamine was being used in small doses to deal with mental health issues like schizophrenia and depression. The use of this drug in dealing with mental issues was seen was a huge breakthrough. However, like all substances, there was of course the recreational side. People were finding ways of making Ketamine and selling it on the black market. This is perhaps where Ketamine gets a negative reputation from. 

Ket: How Does It Make You Feel?

Now you understand the history of Ketamine, what it is, and what it might be used for, the question still remains: what does it feel like? Ketamine is a hugely popular drug both in the medic world and recreationally. When used recreationally, ketamine lasts around 30-60 minutes, and takes about 10 minutes to kick in. 

Positive Effects

  • The feeling of euphoria
  • Positive dissociation
  • Slows down time 
  • Allows you to concentrate
  • Physical pains subside 
  • Mental pains subside 
  • Funny and elaborate thoughts 

Negative Effects

  • Agitation 
  • Panic attacks 
  • Short-term or long-term memory loss 
  • Negative dissociation 
  • Can become addictive 
  • Can feel depressed without it 
  • You can feel invincible, which could lead to harming yourself
  • K-holing 

The K-Hole 

Anyone who knows about ketamine will have heard of the infamous ‘k-hole’. Now some people enjoy the k-hole, whilst others fear it. It’s sort of like the ‘whitey’ in the world of cannabis. A k-hole occurs when someone takes too much Ketamine. Due to the strength of Ketamine powder, it’s very easy to take too much or become unaware of how much you’ve taken due to anesthetic feeling of the drug. Therefore, k-holes are actually a lot more common than you’d think. The feeling of a k-hole is peculiar. All of those feelings of being outside your body, unable to move freely, and feeling slow, all become extremely strong and sort of paralyze you. It usually feels like it’s lasting hours, when actually it only lasts 30 or so minutes. Ultimately, It isn’t a very pleasant feeling. However, if you’ve got someone around you that you can trust then you should be fine. 

Is Ketamine Legal?

Ketamine, much like the majority of drugs, is used in medicines and in doctor’s practices but is illegal to use recreationally. In the UK, it is a Class B drug, which is the same as cannabis. In the US, ketamine is also illegal and is a Schedule III substance under the Controlled Substances Act. 

According to the DEA, Ketamine is illegal because it has the potential for abuse. But, on the positive side, in 2019 the…

“FDA approved…Ketamine nasal spray for treatment-resistant depression”

This is a potential positive. Whilst Ketamine is illegal in most major countries, research is definitely being done into how it can be used to help people with mental conditions. 

Ket: My Own Experiences

I always like to include my own experiences of the drugs I write about in this series, just so it doesn’t sound like someone who hasn’t himself had his own dealings with Ketamine. I always hate reading about drugs on websites where I know, quite clearly, that that person has never touched a drop in their life. So what do I think about Ketamine? 

Well, university was when I had my first dealings with Ketamine; or ‘Ket’ as everyone called it. I was drunk at a very un-cool club night and someone gave me a bag full of white powder and told me to go take a ‘key’ of it. At the time, I didn’t actually know what a ‘key’ was. I imagined you just placed as much powder on a key as you could. I also didn’t want to risk asking and seeming inexperienced. Oh the wonders of peer pressure! So I snuck into the bathroom, got out the baggy, got out my key, and put the key inside. I placed, what I thought, was the right amount of Ket onto the key (which ended up being far far too much) and tried my best to snort it up my nose. I then went back on the dance floor, unaware that my nose now had a huge amount of white powder quite blatantly stuck to it. 

For about 30 minutes I felt nothing, and continued to drink and dance with my friends. However, as the minutes went past, I began to feel heavier. I felt amazing. The music slowed down, I slowed down, everyone slowed down. My limbs began to feel like warm pillows and all the negative thoughts in my head left me. It wasn’t the same euphoric feeling of ecstasy, but I still felt good.

However, after a while I realized I’d obviously taken too much. Time didn’t just go slow, it basically stopped. That’s when I remember thinking ‘I’m gonna die’. Which, to be fair, was a classic thought I had when I took most drugs at that age. I then don’t really remember much. It felt like I was stuck in time for hours, but it later turned out to only be about 20 minutes. I just remember sort of regaining consciousness outside in the smoking area, with my friend chatting to me about the price of plastic bags. A very odd experience. I then continued my night and just had very elaborate, comical thoughts. It was definitely a mixed first experience. Although I will add, that now I know how much Ketamine to have, I do find it a very amusing drug; and one with the least negative sides. 

What’s Your Opinion?

So, what do you think? Do you think Ketamine is a drug that deserves more research and consideration? Or is its recreational abuse proof that it should be regulated forever? As always, we want to know what you think, drop us a line in the comment section below. Make sure to keep up to date with the rest of the articles in this series as we go through all of the most popular street drugs. Until next time.

Thank you for stopping by CBD TESTERS, your hub for all things cannabis-related. Remember to subscribe to The Delta 8 Weekly Newsletter for more articles like this one and exclusive deals on flowers, edibles, vapes, and other legal products.





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Wesana Health to Acquire PsyTech, Emphasizing Shift to Psychedelics

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If you haven’t been paying attention, medical psychedelics are on the rise, with the new industry gaining an impressive foothold even before legalizations occur. In this new move, Wesana Health will acquire Psytech, Inc., giving the company new strength to dominate this new emerging market.

The world changes quickly. Not only is Wesana Health about to acquire PsyTech, Inc., signaling even more growth in the medical psychedelics industry, but our favorite psychedelic – cannabis – has more options for consumers than ever. Take Delta 10, THCV, THC-O or Delta-8 THC for example. This half-brother of delta-9 THC provides users with a slightly less intense psychoactive high, doesn’t produce anxiety, and leaves users clear-headed and energetic. This is amazing for anyone who wants a different option. Check out our array of delta-8 THC products – along with tons of other compounds offered, and take advantage of new drug technologies and formulations.

Wesana will acquire Psytech, Inc., what will this mean?

Wesana Health Holdings, is a life sciences company that specializes in developing and delivering therapies for neurological health issues. The Chicago-based company looks to help patients overcome the damage of physical brain trauma which results in neurological, psychological, and mental health problems. The company was founded recently, in 2020, and looks to develop therapeutic solutions using psychedelic therapies including drugs like: Ketamine (and esketamine, which is currently legal), mescaline, MDMA, and psilocybin.

Psychedelitech, Inc. (PsyTech, Inc.) is a company specializing in the medical psychedelics industry, which provides clinical tools and education, as well as clinical care. The company promotes psychedelic-assisted therapy, novel methods of care and the tools to go along with them, and integrative ways for mental healthcare delivery. The company focuses a lot on the use of psilocybin therapies. The company has three parts: Tovana Solutions – a SaaS platform, Tovana Clinics – which provides a psychiatric care network, and PsyTech Connect – a community for psychedelic practitioners.

It was announced on June 13th, 2021, that Wesana Health would acquire PsyTech for $21 million, making PsyTech a completely owned subsidiary of Wesana. This will give Wesana access to all three parts of PsyTech. Wesana is looking to expand its efforts into neurological healthcare. According to CEO Daniel Carcillo (who is also a former NHL hockey player and two-time winner of the Stanley Cup), Wesana is working on new treatments and medications to treat traumatic brain injuries. He made this statement about the acquisition:

medical psychedelics

“The acquisition of PsyTech will greatly accelerate our ability to understand, analyze and improve neurological health and performance by providing a data platform on which to build our technical strategy, clinics in which to apply and accelerate our neuroscience research and relationships with many thousands of the practitioners who will leverage our medicines, diagnostics, and technology to heal people.”

The three arms of PsyTech

PsyTech has three components that Wesana will be taking over. Tovana Clinics – soon to be Wesana Clinics is a chain of mental health clinics which specialize in the delivery of psychedelic-based care, which currently involves esketamine therapy (as this is the only currently legalized psychedelic medication), and looks to incorporate new compounds as they become legal. The chain currently involves two locations, with a third set to open later this year, and about 12 more in the works that should be operational by this time next year.

PsyTech’s Tovana Solutions platform provides data collection, tracking in real-time, patient management, and general analysis tools. It also provides healthcare professionals the ability to learn current protocols and track effectiveness. The platform will be renamed Wesana Solutions.

The last arm, PsyTech Connect, is a network of over 8,000 professionals who tune in to find out about best clinical practices and protocols. Besides the network of practitioners, it also provides conferences, and educational material. The idea for Wesana is to integrate with psychiatrists across the US to expand the company and its therapeutic model.

Wesana founder and Executive Chairman, Chad Bronstein, reminds: “There are over 50,000 psychiatrists and 15,000 psychiatric practices in North America alone who will require solutions to adopt the novel and effective psychedelic-assisted therapies that already exist and are currently in development.”

Both the boards of Wesana and PsyTech have approved the acquisition unanimously. In order for it to officially go through, 2/3 of PsyTech’s shareholders must also approve. With 67% of shareholders already signed onto an agreement of support for the measure, there shouldn’t be anything getting in the way of the acquisition happening.

What psychedelic medications are already used?

Esketamine therapy

The medical psychedelic movement is massively picking up speed, even if it hasn’t quite filtered through to mainstream media just yet. There are, by the way, reasons that news of this industry’s growth hasn’t made major headlines in major publications. As of right now, there are a lot of smaller biotech companies like Wesana and PsyTech getting in on it, and that means competition for the major pharmaceutical companies, which so far do have the only legal offering. Until large pharmaceutical companies can fully profit off the industry, I expect it will be kept quiet, despite major growth.

So what is currently legal? Only one medication is out called esketamine. What is this compound? Esketamine, as the name implies, is a close relative of the dissociative and psychedelic party drug, (and animal tranquiller and human anesthetic), ketamine. In 2019 the FDA approved esketamine for treatment for major depression.

In 2020, the FDA updated the approval to cover prescription for suicidal thoughts as well because of how fast-acting the compound is. Esketamine is the first new medication approval for depression which does not fit the standard model of antidepressants, as its not an SSRI, tricyclic antidepressant, or MAO inhibitor. In fact, it entirely goes against the current model for the treatment of mental illness, meaning it does not work with monoamines.

Esketamine is sold under the name Spravato, being marketed by Johnson & Johnson’s Janssen Pharmaceutical Companies. It has been approved as an anesthetic under other trade names like ketanest. Esketamine is a Schedule III substance in the US.

What psychedelic medications are on the way?

Obviously, if one psychedelic drug has been approved, which already breaks with the idea that all psychedelics are illegal (obviously not the case), then why shouldn’t it be expected that more are on the way? In fact, they most certainly are, and to show how clear it is these legalizations are coming, the US government is actually pushing for them through its own Food & Drug Administration. In fact, the two compounds its currently pushing, are specifically Schedule I drugs at the moment, but will not be for much longer. Here’s why:

In 2017, the FDA earmarked the drug MDMA as a ‘breakthrough therapy’ for the treatment of PTSD. What does this term mean? According to the FDA, “A breakthrough therapy designation is for a drug that treats a serious or life-threatening condition and preliminary clinical evidence indicates that the drug may demonstrate substantial improvement on a clinically significant endpoint(s) over available therapies.” This designation isn’t blindly made, but generally comes at the request of a drug company, which is currently doing research that shows the compound is more promising than current options.

mdma therapy

This description is meant to quicken research and get products to market faster. What this means, is that the FDA is pushing for a Schedule I substance – defined as a highly dangerous compound with no therapeutic value, to be on pharmacy shelves sooner, rather than later. To make it even more clear, the Multidisciplinary Association for Psychedelic Studies (MAPS) – which is the organization that won the designation for its research, is currently in phase 3 trials for an MDMA drug, which were put together in conjunction with the FDA to ensure the trials and outcomes would be in line with FDA regulation. Is there a better way to say the US government wants this drug out to consumers?

The thing is, MDMA isn’t the only drug being backhandedly pushed by the US government. In 2019, the FDA gave two separate ‘breakthrough therapy’ titles to psilocybin from magic mushrooms, for use with major depressive disorder. The first granting of this designation was given to Compass Pathways, which looks to treat the most severe treatment-resistant depression, and the second time around it went to Usona Institute, which has ongoing trials to test the efficacy of just one dose of psilocybin to treat major depression.

Conclusion

That Wesana Health is about to acquire PsyTech, is just another indication of the growing magnitude of this new industry. The acquisition also highlights not only the growing appeal of psychedelic compounds to treat mental illness, but of the networks now being put together, which will set up the entire framework of how these therapeutic services will run.

Hello and welcome! You’ve arrived at CBDtesters.co, your #1 spot for all the most thought provoking, and relevant cannabis-related news globally. Take a read-thru of the site daily to stay abreast of what’s happening in the exciting universe of legal cannabis and medical psychedelics, and sign up for our newsletter, so you never miss a thing.

DisclaimerHi, I’m a researcher and writer. I’m not a doctor, lawyer, or businessperson. All information in my articles is sourced and referenced, and all opinions stated are mine. I am not giving anyone advise, and though I am more than happy to discuss topics, should someone have a further question or concern, they should seek guidance from a relevant professional.





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